HISTONE DEACETYLASE 6 INTERFERENCE PROTECTS MICE AGAINST EXPERIMENTAL STROKE-INDUCED BRAIN INJURY VIA ACTIVATING NRF2/HO-1 PATHWAY

Histone deacetylase 6 interference protects mice against experimental stroke-induced brain injury via activating Nrf2/HO-1 pathway

Cerebral stroke is a fatal disease with increasing incidence.The study was to investigate the role and mechanism of Histone deacetylase 6 (HDAC6) on experimental stroke-induced brain injury.The recombinant shRNA-HDAC6 or scramble shRNA lentivirus was transfected to ICR mice.Then, the ischemia/reperfusion injury (I/RI) mice were constructed using mi

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A new time

The article presents the results of the first Bayesian model of a causewayed enclosure from Denmark.21 samples were dated, some with multiple dates, giving a total of 41 dates.These dates are built into a model Optimiser which includes archaeological priors in the form of stratigraphy.It is demonstrated that this enclosure can be dated to the same

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Do major roads reduce gene flow in urban bird populations?

Although the negative effects of roads on the genetics of animal populations have been extensively reported, the question of whether roads reduce gene flow in volant, urban bird populations has so far not been addressed.In this study, we assess whether highways decreased gene flow CPO-TW and genetic variation in a small passerine bird, the tree spa

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